AM-694

$320.00$3,200.00

What is  AM-694?

AM-694 is a potent synthetic cannabinoid (CB) that primarily acts as a selective agonist for the cannabinoid receptor CB1. Pure AM-694 for sale.

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Description

Pure AM-694 Available For Sale

What is  AM-694?

AM-694 is a potent synthetic cannabinoid (CB) that primarily acts as a selective agonist for the cannabinoid receptor CB1. Pure AM-694 for sale.

AM-694 Chemical Properties, Pure AM-694 for sale

Molecular FormulaC20H19FINO

Average mass435.274 Da

Monoisotopic mass435.049530 Da

Long-term Storage: 2 to 8 °C, dark
Appearance: white solid
Melting Point: 104 °C

Effects and Toxicity

AM694 can be smoke or ingest orally. 1-3 mg is sufficient to produce effects; however, in a self-administration experiment following oral (10 mg) and smoke (1 mg in 1mL acetone) administration, physiological effects were also study.

Pharmacology

AM-694 is an agonist for cannabinoid receptors. It has a Ki of 0.08 nM at CB1 and 18 times selectivity over CB2 with a Ki of 1.44 nM.

It is unclear what is responsible for this unusually high CB1 binding affinity, but it makes the 18F radiolabel derivative of AM-694 useful for mapping the distribution of CB1 receptors in the body.

The physiological actions and metabolism of AM694 have not been characterize.

AM-694 or 1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole is a synthetic cannabinoid that acts as a selective

A powerful agonist for CB1 receptor, inducing cannabinoid-like effects (euphoria, sedation, hallucinations and anxiety).

In other words its spread, like for other synthetic cannabinoids, has increased in recent years and many web sources freely supply these kinds of new substance.

Similarly it can be administer by smoking or through oral consumption. A 25-years-old man was hospitalize at the local hospital following a major trauma after ingestion of alcohol and also an unknown pill.

Also urine and blood samples were sent to our Forensic Toxicology Division to investigate on possible substance abuse.

However a general  screening of biological samples, extract by liquid-liquid extraction (ethylacetate and dichloromethane) in basic, acidic and neutral conditions, was achieve to verify the presence of drugs of abuse and/or their metabolites, both in gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS).

As a result for the quantification of AM-694, urine was extracted by solid phase extraction (SPE) on a Bond Elut Certify cartridge; Above all an acidic hydrolysis (HCl 30%, 95°C, 60min) was necessary before liquid-liquid extraction of metabolites.

 

Additional information

AM-694

20 g $ 320, 500 g $ 680, 100 g $ 1200, 250g $ 1800, 1 kg $ 3200

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