Description

Best Quality AM-1221 for Sale for Large Orders

What is AM-1221?

AM-1221 is  a potent and selective agonist for the cannabinoid receptor CB₂, with a K_i of 0.28 nM at CB₂ and 52.3 nM at the CB₁ receptor, giving it around 180 times selectivity for CB_{2.  AM-1221 for Sale .}

Product Information ,AM-1221 for Sale

• Molecular FormulaC₂₆H₂₅N₃O₃
• Average mass427.495 Da
• Monoisotopic mass427.189606 Da

The 2-methyl and 6-nitro groups on the indole ring both tend to increase CB₂ affinity while generally reducing affinity at CB₁, explaining the high CB₂ selectivity of AM-1221.

However, despite this relatively high selectivity for CB₂, its CB₁ affinity is still too strong to make it useful as a truly selective CB₂ agonist, so the related compound AM-1241 is generally prefer

for research purposes.

Typical effects include

1. Feelings of being happy, euphoric and relaxed, with some people gettings the giggles, feeling hunger pangs and becoming very talkative, while others get more drowsy.
2. Mood and perception can change, and concentration and coordination may become difficult. Synthetic cannabinoids, possibly because of their potency, are more likely to be associated with hallucinations than natural cannabis.
3. Some will have quite bad reactions, such as paranoia, panic attacks and forgetfulness.

Duration

How long the effects last and the drug stays in your system depends on how much you’ve taken, your size and what other drugs you may have also taken.

Physical health risks